As a common centrifugal pump, the self-priming pump has the advantages of compact structure, easy operation and stable operation. It is widely used in power, chemical, metallurgy, environmental protection and other industries. However, in the actual operation process, some self-priming pumps will have the problem of large sound and vibration, which not only affects the normal operation of the equipment, but also may cause noise pollution to the surrounding environment. Therefore, it is of great practical significance to study the causes and solutions of the large sound and vibration of the self-priming pump.